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Modern medicinal chemistry / John B. Taylor and Peter D. Kennewell.

By: Contributor(s): Material type: TextTextSeries: Ellis Horwood series in pharmaceutical technologyPublication details: New York ; London : Ellis Horwood, 1993.Description: xi, 290pISBN:
  • 9780135903995 (pbk) :
  • 0135903998
Subject(s): DDC classification:
  • 615.1 TAY
Contents:
Definitions -- Drug development -- Scene today -- Major processes of drug action -- Pharmaceutical phase -- Introduction to biopharmaceutics -- Physicochemical principles -- Formulation science -- Routes of administration of medicines -- Controlled release dosage forms -- Pharmacokinetic phase -- Absorption processes -- Distribution -- Clearance -- Sites of drug metabolism -- Biotransformation -- Metabolic pathways -- Pharmacodynamic phase -- Cell structures -- Cell membrane -- Receptor theories -- Types of binding in drug-receptor interactions -- Use of radio-labelled ligands -- Isolation of receptors -- Primary and secondary messengers -- Intracellular proteinaceous receptors -- DNA as a receptor -- Enzymes -- Drug discovery processes -- Sources of lead structures -- Macromolecular targets for drug design -- Computational chemistry -- Computer graphics -- Modelling drug-receptor interactions -- Drug design methods -- Applications of drug design techniques -- Optimisation of lead structures.
Summary: An introduction to medicinal chemistry including computing and other modern techniques. The main objective of medicinal chemistry is the design and synthesis of new medicines, and this book covers widely this rapidly developing and important field of chemistry.
Holdings
Item type Current library Call number Copy number Status Date due Barcode
Long Loan TUS: Midlands, Main Library Athlone General Lending 615.1 TAY (Browse shelf(Opens below)) 1 Available 101719
Short Loan TUS: Midlands, Main Library Athlone General Lending 615.1 TAY (Browse shelf(Opens below)) 1 Available 100716

Includes bibliographical references (p. [281]-285) and index.

Definitions -- Drug development -- Scene today -- Major processes of drug action -- Pharmaceutical phase -- Introduction to biopharmaceutics -- Physicochemical principles -- Formulation science -- Routes of administration of medicines -- Controlled release dosage forms -- Pharmacokinetic phase -- Absorption processes -- Distribution -- Clearance -- Sites of drug metabolism -- Biotransformation -- Metabolic pathways -- Pharmacodynamic phase -- Cell structures -- Cell membrane -- Receptor theories -- Types of binding in drug-receptor interactions -- Use of radio-labelled ligands -- Isolation of receptors -- Primary and secondary messengers -- Intracellular proteinaceous receptors -- DNA as a receptor -- Enzymes -- Drug discovery processes -- Sources of lead structures -- Macromolecular targets for drug design -- Computational chemistry -- Computer graphics -- Modelling drug-receptor interactions -- Drug design methods -- Applications of drug design techniques -- Optimisation of lead structures.

An introduction to medicinal chemistry including computing and other modern techniques. The main objective of medicinal chemistry is the design and synthesis of new medicines, and this book covers widely this rapidly developing and important field of chemistry.

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