Modern medicinal chemistry /
Taylor, J. B. 1938-
Modern medicinal chemistry / John B. Taylor and Peter D. Kennewell. - New York ; London : Ellis Horwood, 1993. - xi, 290p. - Ellis Horwood series in pharmaceutical technology .
Includes bibliographical references (p. [281]-285) and index.
Definitions -- Drug development -- Scene today -- Major processes of drug action -- Pharmaceutical phase -- Introduction to biopharmaceutics -- Physicochemical principles -- Formulation science -- Routes of administration of medicines -- Controlled release dosage forms -- Pharmacokinetic phase -- Absorption processes -- Distribution -- Clearance -- Sites of drug metabolism -- Biotransformation -- Metabolic pathways -- Pharmacodynamic phase -- Cell structures -- Cell membrane -- Receptor theories -- Types of binding in drug-receptor interactions -- Use of radio-labelled ligands -- Isolation of receptors -- Primary and secondary messengers -- Intracellular proteinaceous receptors -- DNA as a receptor -- Enzymes -- Drug discovery processes -- Sources of lead structures -- Macromolecular targets for drug design -- Computational chemistry -- Computer graphics -- Modelling drug-receptor interactions -- Drug design methods -- Applications of drug design techniques -- Optimisation of lead structures.
An introduction to medicinal chemistry including computing and other modern techniques. The main objective of medicinal chemistry is the design and synthesis of new medicines, and this book covers widely this rapidly developing and important field of chemistry.
9780135903995 (pbk) : £24.95 0135903998
92239486
Pharmaceutical chemistry.
Biotechnology
Chemistry
Pharmacology
Chemistry, Pharmaceutical.
Pharmacokinetics.
Pharmacology.
Drugs
615.1 TAY
Modern medicinal chemistry / John B. Taylor and Peter D. Kennewell. - New York ; London : Ellis Horwood, 1993. - xi, 290p. - Ellis Horwood series in pharmaceutical technology .
Includes bibliographical references (p. [281]-285) and index.
Definitions -- Drug development -- Scene today -- Major processes of drug action -- Pharmaceutical phase -- Introduction to biopharmaceutics -- Physicochemical principles -- Formulation science -- Routes of administration of medicines -- Controlled release dosage forms -- Pharmacokinetic phase -- Absorption processes -- Distribution -- Clearance -- Sites of drug metabolism -- Biotransformation -- Metabolic pathways -- Pharmacodynamic phase -- Cell structures -- Cell membrane -- Receptor theories -- Types of binding in drug-receptor interactions -- Use of radio-labelled ligands -- Isolation of receptors -- Primary and secondary messengers -- Intracellular proteinaceous receptors -- DNA as a receptor -- Enzymes -- Drug discovery processes -- Sources of lead structures -- Macromolecular targets for drug design -- Computational chemistry -- Computer graphics -- Modelling drug-receptor interactions -- Drug design methods -- Applications of drug design techniques -- Optimisation of lead structures.
An introduction to medicinal chemistry including computing and other modern techniques. The main objective of medicinal chemistry is the design and synthesis of new medicines, and this book covers widely this rapidly developing and important field of chemistry.
9780135903995 (pbk) : £24.95 0135903998
92239486
Pharmaceutical chemistry.
Biotechnology
Chemistry
Pharmacology
Chemistry, Pharmaceutical.
Pharmacokinetics.
Pharmacology.
Drugs
615.1 TAY