Sample preparation in LC-MS bioanalysis / edited by Wenkui Li, Wenying Jian, and Yunlin Fu.

Includes bibliographical references and index.

Part I.Current sample preparation techniques in LC-MS bioanalysis, 1.Basic sample preparation techniques in LC-MS bioanalysis: protein precipitation, liquid-liquid extraction, and solid-phase extraction. 2.Online extraction and column switching techniques in LC-MS bioanalysis. 3.Equilibrium dialysis, ultracentrifugation, and ultrafiltration in LC-MS bioanlysis. 4,Phospholipid depletion techniques in LC-MS bioanalysis. 6.Supported liquid extraction (SLE) in LC-MS bioanalysis. 7.Immunocapture in LC-MS bioanalysis. 8.Microextraction techniques in LC-MS bioanalysis. 9.Microsampling applications with LC-MS bioanalysis. 10.Nanomaterials for sample preparation in LC-MS bioanalysis. 11.Sample preparation via molecularly imprinted polymers (MIPs). 12.Stir-bar sorptive extraction for sample preparation in LC-MS bioanalysis. 13.Monolithic spin column extraction in LC-MS bioanalysis. 14.A[ta,er-based sample preparaton in LC-MS bioanlysis. 15.Sample extraction via electromemberane in LC-MS bioanalysis. Part II.Matrix-specific preparation techniques in LC-MS bioanalysis. 17.Sample preparaton for LC-MS bioanalysis fo peripheral blood mononuclear cells. 18.Sample preparation for LC-MS bioanalysis of uringe, cerebrospinal fluid, synovial fluid, sweat, tears and acqueous humor samples. 19.Sample preparation for LC-MS bioanalysis of liposomal samples. Part III.Sample preparation techniquest for LC-MS bioanalysis of challenging molecues. 20.Key pre-analytical considerations in LC-MS bioanalysis. 21.Derivatization in sample preparation for LC-MS bioanalysis 22.Sample preparation for LC-MS bianalysis of lipids. 23.Sample preparation for LC-MS bioanalysis of peptides. 24.Sample prepartion for LC-MS bioanaysis of proteins. 25.Sample preparation for LC-MS bioanalysis of oligonucleotides. 26.Sample preparation for LC-MS bioanalysis of antibody-drug conjugates.