Cryptosporidium : from molecules to disease / edited by R.C.A. Thompson, A. Armson and U.M. Ryan.

The incidence of Cryptosporidium and Giardia in Private Water Supplies in the United Kingdom-- 52. The problem with Cryptosporidium in Swimming Pools-53. Development of a Standard Method to Recover Protozoan Parasites from soft fruit and salad vegetables--54. How safe is drinking water in Primary schools?--55. Cryptosporidium parvum Oocyst recovery using Immunomagnetizable Separation--56. Significance of Enhanced Morphological Detection of Cryptosporidium sp. Oocysts in water concentrates using DAPI and Immunofluorescence Microscopy--57. Surveillance of Cryptosporidiosis: Progressive approaches--58. Cryptosporidium and the environment - Overview and summary--SECTION 9: Cryptosporidium - Chemotherapy:- 59. A review of Chemotherapeutic approaches to the treatment of Cryptosporidium-- SECTION 10: Extended Abstracts:- 60. An examination of the activity of the Dinitroanilines on Cryptosporidium parvum using In Vitro, In vivo and Target Expression methods--61. Nitazoxanide in the treatment of cryptosporidiosis--62. The Application of quantitative-PCR for high throughput screening of novel compounds against Cryptosporidium parvum in vitro and their subsequent IC50 Determination--SECTION 11: Synthesis:- Facilitators.

SECTION 1:Cryptosporidiosis-aetiology, infectivity and pathogenesis:-1. Cryptosporidium: They probably taste like Chicken: Introduction--Species in the genus Cryptosporidium--C.parvum in cattle--Conclusion---Acknowledgments--References--2. Cryptosporidium: From Molecules to Disease:- -- Introduction--The disease--Widespread recognition of the disease--Application of molecular techniques to diagnosis and detection--Identification and naming of species--History--The complex epidemiological picture emerging from molecular data--Application of molecular tools to future Cryptosporidium research--References--3. Cryptosporidium parvum: Infectivity, Pathogenesis and the Host-Parasite Relationship--4. What is the Clinical and Zoonotic Significance of Cryptosporidiosis in Domestic Animals and Wildlife--SECTION 2: Extended Abstracts:- 5. Control of Cryptosporidium parvum infection and the role of IL-4 in Two Strains of Inbred Mice--6. Human Peripheral CD8+CD103+ T-Lymphocyte Transmigration through inverted Cryptosporidium parvum Sporozoite Infected HCT-8 Cell Monolayers--7. Cryptosporidium parvum Volunteer Study: Infectivity and Immunity--8. Experimental Transmission of Human Genotype 1 Cryptosporidium parvum into lambs--9. A Longitudinal study of Cryptosporidium Prevalence and its Impact on performance in feedlot cattle--10. Identification and characterisation of the Antigenic Cpa135 Protein--11. A Permanent method for detecting Cryptosporidium parvum Life Cycle Stages in In Vitro Culture--12. Successful cultivation of Cryptosporidium reveals previously undescribed gregarine-like developmental stages--SECTION 3: Eqidemiology and Species Differentiation:- 13. Cryptosporidium as a Public Health Challenge--14. The Zoonotic Potential of Cryptosporidium--15. Molecular Epidemiology of Human Cryptosporidiosis--16. Molecular Characterization and Taxonomy of Cryptosporidium--SECTION 4: Extended Abstracts:- 17. Antigenic Differences in Cryptosporidium parvum Oocysts: The IOWA Strain Enigma--18. Antigenic Analysis of Cryptosporidium parvum Isolates of Human and Animal Origin--19. Typing of Cryptosporidium parvum Oocysts using Phage-Display Technology--20. High Resolution Genotyping of Cryptosporidium by Mutation Scanning--21. Evaluation of Oocyst DNA Extraction Methods Using Real-time PCR--22. Differentiation of Cryptosporidium parvum Subtypes by a Novel Microsatelite-telomere PCR with page--23. Genotypic Variation of Cryptospridium Organisms recovered from Persons living in Kenys, Malawi, Vietnam and Brazil--24. Epidemiological Surveys of Cryptosporidiosis in Thai

Orphans--25. Cryptosporidium and Cyclospora-Associated Diarrhea in Kathmandu, Nepal--26. Ecology of Zoonotic Cryptosporidiosis in Watersheds containing cattle farming operations--27. Identifying variation among human, animal and environmental isolates of Cryptosporidium--28. Cryptosporidium in Eastern Grey Kangaroos macropus giganteus--SECTION 5: Viability and Infectivity:- --29. Detection of Infectious Cryptosporidium parvum Oocysts in Environmental Water Samples--30. Measuring Inactivation of Crystoporidium parvum by In Vitro Cell Culture--31. In Vitro Cultivation and Development of Cryptosporidium in Cell Culture--SECTION 6: Extended Abstracts:- 32. The Use of Cell Culture and Real-Time PCR to Assess Disinfection of Cryptosporidium parvum--33. Inactivation of Cryptosporidium parvum Oocysts by Low Pressure UV-Light--34. Detection of Viable Oocysts of Cryptosporidium parvum by Nucleic Acid Sequence based Amplification (NASBA)--35. Flow Cytometry Evaluation of Cryptosporidium parvuum Oocyst viability--SECTION 7: Cryptosporidium and the Environment:- 36. The public Health significance of Cryptosporidium in the environment--37. Assessing variables in disinfection parameters of Cryptosporidium parvum Oocysts--38. Detection of Cryptosporidium Oocysts in water matrices--39. Microbiological Health Criteria for Cryptosporidium--40. Case-control studies of sporadic cryptosporidiosis in Melbourne and Adelaide--41. The DWI licensed inter-laboratory Cryptosporidium proficiency scheme (CRYPTS)--SECTION 8: Extended Abstracts:- 42. Detection of Cryptosporidium spp.via fluorescent in situ Hybridization: Novel approache of background reduction and signal enhancement--43. The Risk of Cryptosporidium to Sydney\'s drinking water supply--44. Outbreak of waterborne cryptosporidiosis at North Battleford, SK, Canada--45. Event sampling for Cryptosporidium and Giardia in South Australian water sources--46. Drinking water regulations for Cryptosporidium in England and Wales--47. Why Cryptosporidium research for large water supplies: Investigations in the Lake Mornos, the big water Reservoir of Greater Athens, Greece--48. Use of Ferric Sulfate Flocculation Method for the Recovery of Cryptosporidium Oocysts from drinking water--50. A Sensitive, Semi-Quantitative Direct PCR-RFLP Assay for Simultaneous Detection of Five Cryptosporidium Species in Treated Drinking Waters and Mineral Waters--51.

In the short period since cryptosporidium was recognised as a human pathogen, & that it could be transmitted in water as well as directly between animals & people, it has been the subject of investigations. This text reviews major advances in research & identifies important research priorities for the future.