Growth factors : a practical approach /
edited by Ian McKay and Irene Leigh.
- IRL, c1993.
- xx,251p.
- Practical approach series ; 119 .
- Practical approach series ; no. 119 .
Includes bibliographical references and index.
(cont) Immunoassays for growth factors / Stephen J. Capper -- Determination of growth factor receptor distribution by immunocytochemistry or autoradiography, and quantitation by ligand binding or FACS analysis / Claire Linge and Martin R. Green -- Growth factors -- Sources of cell strains and cell lines -- Amino acid abbreviations -- Names and addresses of suppliers. Types of growth factor activity: detection and characterization of new growth factor activities / I.A. McKay -- Detection of polypeptide growth factors: application of specific bio-assays and PCR technology / E.J.J. Van Zoelen ... [et al.] -- Induction of DNA synthesis and cell division in quiescent cells in response to small peptide growth factors / Anthony N. Corps and Kenneth D. Brown -- Novel gene transcription in response to growth factors: gene isolation by differential plaque hybridization / P. Sanjeeva Reddy and Brent H. Cochran -- Embryological assays for growth factors / J.M.W. Slack -- Role of TGF- in bone growth and bone repair / R.T. Ballock and A.B. Roberts -- Localization of growth factor mRNA in tissue sections by in situ hybridization / Rosemary J. Akhurst -- Detection and characterization of growth inhibitory factors: epidermal inhibitory pentapeptide (EIP) / Philip Robinson, Paul Whitehead and William Hume -- Expression of growth factors in microbial systems / Timothy J. Dudgeon, John M. Clements and Michael G. Hunter.
Growth factors play an important role in the regulation of proliferation and differentiation of specific cell types. This is a guide to studying growth factors, from the search for and characterization of new activities, to "in vivo" analysis and molecular biology approaches such as DNA cloning.