TY - BOOK AU - Patrick,Graham L. TI - An introduction to medicinal chemistry SN - 9780199275007 (pbk.) : AV - RS403 U1 - 615.19 PAT PY - 2005/// CY - Oxford PB - Oxford University Press KW - Pharmaceutical chemistry KW - Health and Wellbeing KW - ukslc KW - Organic chemistry KW - thema KW - Medicine & nursing KW - Manufacturing industries KW - Pharmaceutical chemistry & technology KW - Pharmacology N1 - Previous ed.: 2001; Includes bibliographical references and index; 1.Drugs and the medicinal chemist -- 2.The why and the wherefore: drug targets -- 3.Proteins as drug targets -- 4.Proteins as drug target: enzymes -- 6.Proteins as drug targets: receptor structure and signal transduction -- 7.Nucleic acids as drug targets -- 8.Pharmacokinetics and related topics -- 9.Drug discover: finding a lead -- 10.Drug design: optimizing target interactions -- 11.Drug design: optimizing access to the target -- 12.Drug development -- 13.Quantitative structure-activity relationships (QSAR) -- 14.Combinatorial synthesis -- 15.Computers in medicinal chemistry -- 16.Antibacterial agents -- 17.Antiviral agents -- 18.Anticancer agents -- 19.Cholinergics, anticholinergics, and anticholinesterases -- 20.The adrenergic nervous system -- 21.The opium analgesics -- 22.Antiulcer agents N2 - This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug ER -