TY - BOOK AU - Lee,Stan AU - Robinson,Graham AU - Robinson,Graham TI - Process development: fine chemicals from grams to kilograms T2 - Oxford chemistry primers SN - 9780198558248 (pbk) : U1 - 615.19 LEE PY - 1995/// CY - Oxford PB - Oxford University Press KW - Pharmaceutical chemistry KW - Chemistry, Technical KW - Chemical engineering KW - Pharmaceutical chemistry & technology KW - thema KW - Organic chemistry KW - Physical chemistry KW - Drugs KW - Production N1 - Includes index; 1.Introduction -- 2.Scale-up issues -- 3.Environmental and regulatory issues -- 4.Fun with cephalosporins -- 5.Thromboxane antagonistis -- 6.Homochiral thromboxane antagonists -- 7.H2 blockers -- 8.Manufacturing route for cloprostenol sodium -- 9.A potential anti-obesity agent -- 10.Reagents for large-scale operation N2 - Process development bridges the gap between the laboratory synthesis of an organic compound and its industrial manufacture on a large scale. This book uses real examples to show the range of problems which may be encountered in scaling up chemical syntheses and the ways in which they may be overcome ER -