TY - BOOK AU - Saunders,John TI - Top drugs: top synthetic routes T2 - Oxford chemistry primers SN - 9780198501008 (pbk.) : U1 - 615.31 SAU PY - 2000/// CY - Oxford PB - Oxford University Press KW - Synthetic drugs KW - Pharmaceutical chemistry & technology KW - thema KW - Chemistry KW - Biochemistry KW - Psychopharmacology KW - Drug compounding KW - Methods KW - Chemistry, pharmaceutical KW - Pharmaceutical preparations KW - Chemical synthesis N1 - Includes bibliographical references and index; 1.Inhibitors of angiotensin converting enzyme as effective antihypertensive agents -- 2.Blockade of antiotensin-II receptors -- 3.Calcium channel blockers in the treatment of angina and hypertension -- 4.Antagonists of histamine receptors (H2) as anti-ulcer remedies -- 5.Proton pump inhibitors as gastric acid section inhibitors -- 6.Modulation of central serotonin in the treatment of depression -- 7.Hynoptic, anxiolytic, anticonvulsant and muscle relaxant agents: ligands for bensodiazepine receptors -- 8.Another histamine receptor: blockers of the H1 reverse transcriptase -- 10.Quinolones as anti-bacterial DNA gyrase inhibitors N2 - This title allows students to see how the organic chemistry taught in undergraduate courses is applied by medicinal chemists in industry. This book describes briefly how each drug works and then reviews the most efficient routes to their synthesis ER -