Gad, Shayne C.

In vitro toxicology / Shayne C. Gad. - 2nd ed. - Washington, D.C. ; London : Taylor & Francis, 2000. - ix, 410 p. : ill. 24 cm

Previous ed.: 1994.

Includes index.

Introduction -- General principles for In vitro -- Ocular toxicity assessment In vitro toxicology -- In vitro methods to predict skin irritation -- Lethality testing -- In vitro genetic toxicity testing -- Pyrogenicity and muscle irritation -- In vitro models for evaluating developmental toxicity -- Neurotoxicology In vitro -- In vitro assessment of nephrotoxicity -- Primary hepatocyte culture as an In vitro toxicologic system for the liver -- Application of In vitro model systems to study cardiovascular toxicity -- Gastrointestinal toxicology: In vitro test systems -- In vitro immonotoxicology -- Strategy and tactics for employment -- Scientific and regulatory considerations in the development of In vitro techniques in toxicology -- Safety issues in the use of human tissue by In vitro metabolism and toxicology laboratories.

Increased concern over animal welfare has encouraged the development of in vitro models for use in identifying and understanding most forms of toxicity. This volume reviews both the uses and limitations of this now broad range of models.

9781560327691 (hbk.) : �60.00 1560327693 �113.93

00064854


Toxicity testing--In vitro
Scientific equipment, experiments & techniques
Medical toxicology
Neonatal medicine
Biochemistry
Science.
Toxicity Tests--methods
Cells, Cultured--drug effects
Drug Evaluation, Preclinical--methods
Tissue Culture.

RA1199.4.I5

571.951028 GAD 571.951028