Basic toxicology : fundamentals, target organs, and risk assessment /
by Frank C. Lu.
- 3rd ed.
- Washington, DC ; London : Taylor & Francis, c1996.
- xviii, 358p. : ill. ; 23cm.
Previous ed.: 199-
Includes bibliographical references and indexes.
Part 1.General principles of toxicology: 1.General considerations - 2.Absorption, distribution and excretion of toxicants -- 3.Biotransformation of toxicants 4.Toxic effects -- 5.Modifying factors of toxic effects. Part II.Testing procedures for conventional and nontarget organ toxicities: 6.Conventional toxicity studies -- 7.Carcinogenesis -- 8.Mutagenesis -- 9.Developmental toxicology -- 10.Lactation. Part III.Target organs and systems -- 11.Toxicology of the immune system -- 12.Respiratory system: inhalation toxicology -- 13.Toxicology of the liver -- 14.Toxicology of the kidney -- 15.Toxicology of the skin -- 16.Toxicology of the eye -- 17.Toxicology of the nervous system -- 18.Reproductive and cardiovascular systems. Part IV.Toxic substances and risk assessment. 19.Food additives and contaminants -- 20.Toxicity of pesticides -- 21.Toxicity of metals -- 22.Over-the-counter preparations -- 23.Environmental pollutants -- 24.Occupational toxicology -- 25.Toxicologic evaluation: assessment of safety/risk.
This text provides a concise, comprehensive treatment of modern toxicology. New to this edition is coverage of such topics as mechanisms, testing, risk assessment, carcinogenesis, oncogenes, receptors and host/environment interactions.