TY - BOOK AU - Sherwood,Dennis AU - Cooper,Jon AU - Sherwood,Dennis AU - Cooper,Jon (Jonathan B.) TI - Crystals, x-rays and proteins: comprehensive protein crystallography SN - 9780199559046 (hbk.) : AV - QC482.D5 U1 - 612.8 SHE PY - 2010/// CY - Oxford PB - Oxford University Press KW - Proteins KW - Structure KW - X-rays KW - Diffraction KW - X-ray crystallography KW - Analysis KW - Science KW - ukslc KW - Condensed matter physics (liquid state & solid state physics) KW - thema KW - Organic chemistry KW - Biochemistry KW - Molecular biology KW - Crystallography N1 - Update to: Crystals, X-rays, and proteins / Dennis Sherwood. 1976; Includes bibliographical references and index; Part I.Fundamentals -- 1.The crystalline state and its study -- 2.Vector analysis and complex algebra -- 3.Crystal systematics -- 4.Waves and electromagnetic radiation -- 5.Fourier transforms and convolutions -- 6.Diffraction -- Review I -- Part II.Diffraction theory -- 7.Diffraction by one-dimensional obstacles -- 8.Diffraction by a three-dimensional lattice -- 9.The contents of the unit cell -- Review II.Part III.Structure solution -- 10.Experimental techniques: sample preparation -- 11.Experimental techniques: data collection and analysis -- 12.The phase problems and the Patterson function -- 13.Molecular replacement -- 14.Solving the phase problem experimentally -- 15.Refinement -- 16.Complementary diffraction methods -- Review III N2 - Information derived from X-ray crystal structures of biological molecules allows us to explain their functions in living organisms and to develop drugs to treat disease. This book describes the principles and practice of X-ray diffraction as a key technique at the forefront of new discoveries in biology and medicine ER -