Sahu, Saura C.

Toxicogenomics : a powerful tool for toxicity assessment / by Saura Sahu. - Oxford : Wiley-Blackwell, 2008. - 416 p.

Includes bibliographical references and index.

Application of toxicogenomics in drug discovery / Michael Liguori, Amy Ditewig, and Jeffery Waring -- Natural products from medicinal plants and risk assessment / Leila Chekir-Ghedira -- The development of a metabonomic-based drug safety testing paradigm / Muireann Coen ... [et al.] -- Potential uses of toxicogenomic biomarkers in occupational health and risk assessment / Paul A. Nony -- Usefulness of toxicogenomics in the regulatory environment / Daniel Casciano -- Toxicogenomics for regulatory use : the view from the bench / P. Ancian ... [et al.] -- Perspectives on toxicogenomics at the US Environmental Protection Agency / Karen Hamernik ... [et al.]. Mechanistic toxicogenomics : design and analysis of microarray experiments / Kirstin Meyer, Susanne Schwenke, and Johanna M. Beekman -- Analysis and interpretation of toxicogenomic data : biological responses to low, environmentally-relevant doses of toxicants / Julia A. Gosse ... [et al.] -- Principles of data-mining in toxicogenomics / Yoko Hirabayashi and Tohru Inoue -- Design issues in toxicogenomics studies : the application of genomic technologies for mechanistic and predictive research / Woong-Yang Park, Lian Li, and Daehee Kang -- Sources of variability in toxicogenomic assays / Karol Thompson, P. Scott Pine, and Barry Rosenzweig -- Key aspects of toxicogenomic data analysis and interpretation as a safety assessment tool to identify and understand drug-induced toxicity / Antoaneta Vladimirova and Brigitte Ganter -- Toxicogenomics as a tool to assess immunotoxicity / Kirsten Baken ... [et al.] -- Toxicogenomics and ecogenomics for studying endocrine disruption and basic biology / Taisen Iguchi, Hajime Watanabe, and Yoshino Kata -- Gene expression profiling of transplacental arsenic carcinogenesis in mice / Jie Liu ... [et al.] -- Characterization of estrogen active compounds and estrogenic signaling by global gene expression profiling in vitro / Stephanie Simon ... [et al.] -- Escherichia coli stress response as a tool for detection of toxicity / Arindam Mitra, Nabarun Chakraborti, and Suman Mukhopadhyay -- Toxicogenomics in vitro : a powerful tool for screening hepatotoxic potential of food-related products / Saura C. Sahu -- Toxicogenomics approach to drug-induced phospholipidosis / Hiroshi Sawada -- Use of toxicogenomics as an early predictive tool for hepatotoxicity / Laura Suter -- Nutrigenomics : the application of genomic signatures in nutrition-related research / Stamotis Theocharis and Elisavet Gatzidou --

'Toxicogenomics' provides up-to-date state-of-the-art information presented by the recognized experts, and is therefore an authoritative source of current knowledge in this field of research.

9780470518236 (hbk.) : £95.00 9780470518236 (cloth : alk. paper)

2008024100


Toxicity testing.
Genetic toxicology.
Genomics.
Proteomics.
Medical toxicology
Health and Wellbeing.
Toxicogenetics.

RA1224.3

616.042 SAH