TY - BOOK AU - McCance,Kathryn L. AU - Huether,Sue E. AU - Brashers,Valentina L. AU - Rote,Neal S. TI - Pathophysiology: the biologic basis for disease in adults and children SN - 9780323065849 (hbk.) : AV - RB113 .M35 2010 U1 - 616.07 MCC PY - 2010/// CY - Maryland Heights, Mo. PB - Mosby Elsevier KW - Physiology, Pathological KW - Nursing KW - Pathology KW - thema KW - Physiology KW - Health and Wellbeing KW - ukslc KW - Nurses\' Instruction KW - Disease KW - Physiological Phenomena N1 - Previous ed.: 2006; Text on lining papers; Includes bibliographical references and index; PART 1: Central Concepts of Pathophysiology: Cells and Tissues:- UNIT 1: The Cell:-1. Cellular biology -- 2. Altered cellular and tissue biology -- 3. The cellular environment: fluids and electrolytes, acids and bases --UNIT 2: Genes and Gene-Environment Interaction:- 4. Genes and genetic diseases -- 5. Genes, environment, and common diseases --UNIT 3: Mechanisms of self-defense:- 6. Innate immunity: inflammation --7. Adaptive immunity --8. Alterations in immunity and inflammation --9. Infection -- 10. Stress and disease --UNIT IV: Cellular Proliferation: Cancer:- 11. Biology, clinical manifestations, and treatment of cancer --12. Cancer epidemiology --13. Cancer in children--PART 2: Pathophysiologic Alterations: Organs and Systems: UNIT V: The Neurologic System:- 14. Structure and function of the neurologic system --15. Pain, temperature regulation, sleep, and sensory function -- 16. Alterations in cognitive systems, cerebral hemodynamics, and motor function --17. Disorders of the central and peripheral nervous systems and the neuromuscular junction --18. Neurobiology of schizophrenia, mood disorders, and anxiety disorders -- 19. Alterations of neurologic function in children--UNIT VI: The Endocrine System:- 20. Mechanisms of hormonal regulation --21. Alterations of hormonal regulation --UNIT VII: The Reproductive Systems:- 22. Structure and function of the reproductive systems --23. Alterations of the reproductive systems --24. Sexually transmitted infections --UNIT VIII: The Hematologic System:- 25. Structure and function of the hematologic system --26. Alterations of erythrocyte function --27. Alterations of leukocyte, lymphoid, and hemostatic function --28. Alterations of hematologic function in children--UNIT IX: The Cardiovascular and Lymphatic Systems:- 29. Structure and function of the cardiovascular and lymphatic systems --30. Alterations of cardiovascular function --31. Alterations of cardiovascular function in children --UNIT X: The Pulmonary System:- 32. Structure and function of the pulmonary system --33. Alterations of pulmonary function --34. Alterations of pulmonary function in children -- UNIT XI: The Renal and Urologic Systems:- 35. Structure and function of the renal and urologic systems --36. Alterations of renal and urinary tract function --37. Alterations of renal and urinary tract function in children --UNIT XII:The Digestive System:- 38. Structure and function of the digestive system --39. Alterations of digestive function --40. Alterations of digestive function in children --UNIT XIII: The Musculoskeletal System:- 41. Structure and function of the musculoskeletal system --42. Alterations of musculoskeletal function --43. Alterations of musculoskeletal function in children --UNIT XIV: The Integumentary System:- 44. Structure, function, and disorders of the integument --45. Alterations of the integument in children--UNIT XV: Multiple Interacting Systems:- 46. Shock, multiple organ dysfunction syndrome, and burns in adults --47. Shock, multiple organ dysfunction syndrome, and burns in children N2 - This fully updated textbook provides pathophysiology students with a complete knowledge base that includes the latest data from research on environmental and genetic factors that influence the disease process ER -