TY  - BOOK
AU  - Carmen,Andrew
AU  - Hardiman,Gary
TI  - Biochips as pathways to drug discovery
T2  - Drug discovery series
SN  - 9781574444506 (hbk.) :
AV  - R857.B5 B54 2006
U1  - 615.19 CAR 
PY  - 2006///
CY  - Boca Raton, Fla., London
PB  - CRC, Taylor & Francis [distributor]
KW  - Biochips
KW  - Drug development
KW  - Health and Wellbeing
KW  - ukslc
KW  - Medical research
KW  - thema
KW  - Biology, life sciences
KW  - Pharmaceutical chemistry & technology
N1  - Includes bibliographical references; 1.DNA biochips - past, present, and future: an overview. Gary Hardiman and Andrew Carmen -- 2.Three-dimensional hydroarrays: novel microarrays for genomic and proteomic studies.Roberto Fagnani, Pavel Tsinberg, and Tony Pircher -- 3.Biochips in malaria for antiparasitic discovery. Karine Le Roch and Elizabeth Winzeler -- 4.Regional variations in intestintal ATP-binding cassette transporter expression identified with a global error assessment model. David M. Mutch, Anton Petrov, J. Bruce German, Gary Williamson, and Matthew-Alan Roberts -- 5.Toxicogenomics in drug safety evaluation: bridging drug discovery and development. Alex Y, Nie, Michael K. McMillan, and Peter G. Lord -- 6.The next generation of automated microarray platforms for a multiplexed CYP2D6 assya. Phillip Kim et al ... -- 7.Evaluation of skeletal muscle and adipose tissue biopsy procedures for microarray-based gene-expression profiling. M. B. A. van Doorn et al ... -- 8.ChIP-on-Chip: analysis of genomewide protein binding and posttranslational modifications. Daniel Robyr -- 9.DNA microarrays as functional genomics tools for cancer drug discover. Arindam Bhattacharjee -- 10.High-throughput microarray analysis. Sejal Sheth -- 11.Laboratory automation: strategies for high-volume industrial microarray programs. Anton Bittner and Andrew A. Carmen -- 12.Association studies: practical and theoretical considerations for drug discovery, evaluation, and beyond. Richard M. Kliman ... et al -- 13.Approaches for microarray data validation. Sergey E. Ilyin -- 14.Microarray enterprise information management: what is it and why is it important? -- 15.Quality control of microarray data. Huinian Xiao et al ... 16.Micro array data normalization and transformation. Huinian Xiao et al ... -- 17.Amplification strategies and DNA biochips. Barbara Ruggeri et al ... --18.Ribo-SPIA, a rapid isothermal RNA amplification method for gene expression analysis. Alan Dafforn et al ... -- 19.Genomics, transcriptomics, and proteomics: novel detection technologies and drug discovery. Phillip Stafford -- 20.Intellectual property issues for DNA chips and microarrays. Vicki G. Norton -- 21.Biochips: market drivers and commercial prospets. Jing  Xu -- 22.A pharmaceutical perspective for microarrays and biochips: current-market overview and future trends. Lisa Milne
N2  - With perspectives that look ahead to the future of this area, 'Biochips as Pathways to drug Discovery' provides an overview of the current state of biochip technology, examining the effects of biochips on biomedical research and specifically the pharmaceutical industry
ER  -