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An introduction to medicinal chemistry / Graham L. Patrick.

By: Material type: TextTextPublication details: Oxford : Oxford University Press, 2005.Edition: 3rd edDescription: xxvi, 741 p. : ill. ; 25 cmISBN:
  • 9780199275007 (pbk.) :
  • 9780199275007
Subject(s): DDC classification:
  • 615.19 PAT
LOC classification:
  • RS403
Contents:
1.Drugs and the medicinal chemist -- 2.The why and the wherefore: drug targets -- 3.Proteins as drug targets -- 4.Proteins as drug target: enzymes -- 6.Proteins as drug targets: receptor structure and signal transduction -- 7.Nucleic acids as drug targets -- 8.Pharmacokinetics and related topics -- 9.Drug discover: finding a lead -- 10.Drug design: optimizing target interactions -- 11.Drug design: optimizing access to the target -- 12.Drug development -- 13.Quantitative structure-activity relationships (QSAR) -- 14.Combinatorial synthesis -- 15.Computers in medicinal chemistry -- 16.Antibacterial agents -- 17.Antiviral agents -- 18.Anticancer agents -- 19.Cholinergics, anticholinergics, and anticholinesterases -- 20.The adrenergic nervous system -- 21.The opium analgesics -- 22.Antiulcer agents.
Summary: This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.
Holdings
Item type Current library Call number Copy number Status Date due Barcode
Long Loan TUS: Midlands, Main Library Athlone General Lending 615.19 PAT (Browse shelf(Opens below)) 1 Available 207279
Long Loan TUS: Midlands, Main Library Athlone General Lending 615.19 PAT (Browse shelf(Opens below)) 1 Available 207280
Long Loan TUS: Midlands, Main Library Athlone General Lending 615.19 PAT (Browse shelf(Opens below)) 1 Available 207278

Previous ed.: 2001.

Includes bibliographical references and index.

1.Drugs and the medicinal chemist -- 2.The why and the wherefore: drug targets -- 3.Proteins as drug targets -- 4.Proteins as drug target: enzymes -- 6.Proteins as drug targets: receptor structure and signal transduction -- 7.Nucleic acids as drug targets -- 8.Pharmacokinetics and related topics -- 9.Drug discover: finding a lead -- 10.Drug design: optimizing target interactions -- 11.Drug design: optimizing access to the target -- 12.Drug development -- 13.Quantitative structure-activity relationships (QSAR) -- 14.Combinatorial synthesis -- 15.Computers in medicinal chemistry -- 16.Antibacterial agents -- 17.Antiviral agents -- 18.Anticancer agents -- 19.Cholinergics, anticholinergics, and anticholinesterases -- 20.The adrenergic nervous system -- 21.The opium analgesics -- 22.Antiulcer agents.

This volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.

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