Pharmaceutics : drug delivery and targeting / Yvonne Perrie, Thomas Rades.
Material type: TextSeries: FASTtrackPublication details: London : Pharmaceutical Press, 2012.Edition: 2nd edDescription: x, 242 p. : ill. ; 24 cmISBN:- 9780857110596 (pbk.)
- 0857110594 (pbk.)
- 0857110594
- Pharmaceutics : drug delivery and targeting
- 615.1076 PER
- 615.1
Item type | Current library | Call number | Copy number | Status | Date due | Barcode | |
---|---|---|---|---|---|---|---|
Long Loan | TUS: Midlands, Main Library Athlone General Lending | 615.1076 PER (Browse shelf(Opens below)) | 1 | Available | 216097 |
Includes index.
Bibliogr.
Machine generated contents note: 1 Controlling drug delivery -- Introduction -- Differentiating delivery systems according to their physical state -- Differentiating delivery systems according to their route of administration -- Differentiating drug delivery systems according to their mechanism of drug release -- Immediate release -- Modified release -- Drug absorption -- Mechanisms of drug absorption -- Summary -- Self-assessment -- Questions -- Further reading -- 2 Immediate-release drug delivery systems I: Increasing the solubility and dissolution rate of drugs -- Introduction -- Improving drug delivery by increasing the solubility and dissolution rate of the drug -- How to determine the dissolution rate of a drug -- Super disintegrants -- Summary -- Self-assessment -- Questions -- Reference -- Further reading -- 3 Immediate-release drug delivery systems II: Increasing the permeability and absorption of drugs -- Introduction -- Biopharmaceutics Classification System -- maximum absorbable dose -- Drug absorption -- Barriers to drug absorption -- Strategies to overcome the barriers to drug absorption -- Summary -- Self-assessment -- Questions -- Further reading -- 4 Delayed-release drug delivery systems -- Introduction -- Small intestine-specific delivery -- Colon-specific drug delivery -- Summary -- Self-assessment -- Questions -- Further reading -- 5 Sustained-release drug delivery systems -- Introduction -- Suitable drug candidates for sustained-release dosage forms -- Dissolution-based sustained-release dosage forms -- Gastroretentive drug delivery systems -- Diffusion-based sustained-release dosage forms -- Summary -- Self-assessment -- Questions -- Further reading -- 6 Controlled-release dosage forms -- Introduction -- Polymer membrane permeation-controlled systems -- Polymer matrix diffusion-controlled systems -- Activation-modulated controlled drug delivery systems -- Feedback-regulated controlled drug delivery systems -- Conclusions -- Self-assessment -- Questions -- Reference -- Further reading -- 7 Site-directed drug targeting -- General principles of drug targeting -- Requirements for effective drug targeting -- Physiological and biological barriers to drug targeting -- Types of drug targeting -- Cellular uptake and intracellular routing of the drug -- Summary -- Self-assessment -- Questions -- Further reading -- 8 Carriers for drug targeting -- Options for drug targeting systems -- Modification of the drug to promote targeting -- prodrugs -- Soluble macromolecular drug carriers to promote targeting -- Colloidal and particulate drug delivery systems -- Summary -- Self-assessment -- Questions -- Further reading