Elements of biopharmaceutical production.

Modeling of biopharmaceutical processes, part 1: microbial and mammalian unit operations -- Scaling down of biopharmaceutical unit operations, part 1: fermentaiton -- Optimization, scale-up, and validation issues in filtration of biopharmaceuticals, part 1 -- Optimization, scale-up, and validation issues in filtration of biopharmaceuticals, part II -- Filter clogging issues in sterile filtration -- Lifetime studies for membrane reuse: principles and case studies -- Modeling of biopharmaceutical processes. Part 2: process chromatography unit operation -- Resin screeing to optimize chromatographic separations -- Efficiency measurements for chromatography columns -- Process validation: how much to do and when to do it -- Quality by design: industrial case studies on defining and implementing design space for pharmaceutical processes, part 1 -- Quality by design: industrial case studies on defining and implementing design space for pharmaceutical processes, part 2 -- Design space for biotech products -- Applying process analytical technology to biotech unit operations -- Application of multivariate data analysis in biotech processing -- Upcoming technologies to facilitate more efficient biologics manufacturing -- Costing issues in the production of biopharmaceuticals -- Economic analysis as a tool for process development: harvest of a high cell-density fermentation.