Organic synthesis : strategy and control / Paul Wyatt and Stuart Warren.
Material type: TextPublication details: Oxford : Wiley-Blackwell, 2008.Edition: 2nd edDescription: 216 pISBN:- 9780470712375 (hbk.) :
- 547/.2 22
- QD262 .W89 2008
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Ebook | TUS: Midlands, Main Library Athlone Online | eBook (Browse shelf(Opens below)) | Available | ||||
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Long Loan | TUS: Midlands, Main Library Athlone General Lending | 547.2 WAR (Browse shelf(Opens below)) | 1 | Available | 00212470 | ||
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Previous ed.: Hoboken, N.J.: Wiley, 2007.
Includes bibliographical references.
The disconnection approach -- Basic principles : synthons and reagents synthesis of aromatic compounds -- Strategy I : the order of events -- One-group C-X disconnections -- Strategy II : chemoselectivity -- Two-group C-X disconnections -- Strategy III : reversal of polarity, cyclisations, summary of strategy -- Amine synthesis -- Strategy IV : protecting groups -- One group C-C disconnections I : alcohols -- General strategy A : choosing a disconnection -- Strategy V : stereoselectivity A -- One group C-C disconnections II : carbonyl compounds -- Strategy VI : regioselectivity -- Alkene synthesis -- Strategy VII : use of acetylenes (alkines) -- Two-group C-C disconnections I : Diels-Alder reactions -- Strategy VIII : introduction to carbonyl condensations -- Two-group C-C disconnections II : 1,3-difunctionalised compounds -- Strategy IX : control in carbonyl condensations -- Two-group C-C disconnections : 1,5-difunctionalised compounds -- Strategy X : aliphatic nitro compounds in synthesis -- Two-group disconnections IV : 1,2-difunctionalised compounds -- Strategy XI : radical reactions in synthesis -- Two-group disconnection V : 1,4-difunctionalised compounds -- Strategy XII : reconnection -- Two-group C-C disconnections VI : 1,6-diCarbonyl compounds -- General strategy B : strategy of carbonyl disconnections -- Strategy XIII : introduction to ring synthesis : saturated heterocycles -- Three-membered rings -- Strategy XIV : rearrangements in synthesis -- Four-membered rings : photochemistry in synthesis -- Strategy XV : the use of ketenes in synthesis -- Five-membered rings -- Strategy XVI : pericyclic reactions in synthesis : special methods for five-membered rings -- Six-membered rings -- General strategy C : strategy of ring synthesis -- Strategy XVII : stereoselectivity B -- Aromatic heterocycles -- General strategy D : advanced strategy.
This book provides a structured course in retrosynthesis- now an important technique used by generations of organic chemists. Now fully revised and updated with a modern look, 25 years of advances in organic synthesis are reflected with the addition of new examples and synthetic pathways.
Electronic reproduction. Ann Arbor, MI : ProQuest, 2016. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.