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Polymorphism in the pharmaceutical industry / edited by Rolf Hilfiker.

Contributor(s): Material type: TextTextPublication details: Weinheim : Wiley-VCH ; Chichester : John Wiley [distributor], 2006.Description: xix, 414 p. : ill. (some col.) ; 25 cmISBN:
  • 9783527311460 (hbk.) :
  • 9783527311460 (hbk.)
Subject(s): DDC classification:
  • 660.28 HIL
LOC classification:
  • TP156
Contents:
1.Relevance of solid-state properties for pharmaceutical products -- 2.Thermodynamics of polymorphs -- 3.Characterization of polymorphic systems using thermal analysis -- 4.Solid-state NMR spectroscopy -- 5.Vibrational spectroscopic methods in pharmaceutical solid-state characterization -- 6.Crystallography for polymorphs -- 7.Light microscopy -- 8.The importance of solvates -- 9.Physical characterization of hygroscopicity in pharmaceutical solids -- 10.The amorphous state -- 11.Approaches to polymorphism screening -- 12.Salt selection -- 13.Processing-induced phase transformations and their implications on pharmaceutical product quality -- 14.Polymorphism and patents from a chemist\'s point of view -- 15.Scientific considerations of pharmaceutical solid polymorphism in regulatory applications.
Summary: Emphasising why solid-state issues are important, this handbook looks at what approaches to take in order to avoid problems, as well as explaining how to exploit the opportunities in the fields of pharmaceutical, agrochemical and fine chemical industries.
Holdings
Item type Current library Call number Copy number Status Date due Barcode
Long Loan TUS: Midlands, Main Library Athlone General Lending 660.28 HIL (Browse shelf(Opens below)) 1 Available 204189

Includes bibliographical references and index.

1.Relevance of solid-state properties for pharmaceutical products -- 2.Thermodynamics of polymorphs -- 3.Characterization of polymorphic systems using thermal analysis -- 4.Solid-state NMR spectroscopy -- 5.Vibrational spectroscopic methods in pharmaceutical solid-state characterization -- 6.Crystallography for polymorphs -- 7.Light microscopy -- 8.The importance of solvates -- 9.Physical characterization of hygroscopicity in pharmaceutical solids -- 10.The amorphous state -- 11.Approaches to polymorphism screening -- 12.Salt selection -- 13.Processing-induced phase transformations and their implications on pharmaceutical product quality -- 14.Polymorphism and patents from a chemist\'s point of view -- 15.Scientific considerations of pharmaceutical solid polymorphism in regulatory applications.

Emphasising why solid-state issues are important, this handbook looks at what approaches to take in order to avoid problems, as well as explaining how to exploit the opportunities in the fields of pharmaceutical, agrochemical and fine chemical industries.

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