MARC details
| 000 -LEADER |
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| fixed length control field |
03990nam a22004338a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
BDZ0001224301 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
StDuBDS |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20180923141701.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
980317s1998 nyu f 000 0 eng d |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
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| LC control number |
97038036 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780471155188 (hbk.) : |
| Terms of availability |
£60.00 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
0471155187 (cloth : alk. paper) |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
StDuBDS |
| Transcribing agency |
StDuBDS |
| Modifying agency |
StDuBDSZ |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
YQAA |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RS419.C656 1998 |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
HEA |
| Source |
ukslc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MKG |
| Source |
thema |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
TDCW |
| Source |
thema |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
615.19 GOR |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
Combinatorial chemistry and molecular diversity in drug discovery / |
| Statement of responsibility, etc. |
edited by Eric M. Gordon and James F. Kerwin. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
New York ; |
| -- |
Chichester : |
| Name of publisher, distributor, etc. |
Wiley, |
| Date of publication, distribution, etc. |
1998. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
400p. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Part I.Combinatorial chemistry and molecular diversity: an introduction -- 1.Historical overview of the developing field of molecular diversity. John C. Chabala ... -- 2.Strategies in the design and synthesis of chemical libraries. Eric M. Gordon. -- 3.Solid-phase peptide synthesis, lead generation, and optimization. Bruce Seligman, Michael Lebl, Kit S. Lam -- 4.Light-directed chemical synthesis of positionally encoded peptide arays. Jeffrey W. Jacobs ... [et al] -- 5.Conformationally restriced peptide and peptidomimetic libraries. Alex A. Virgilio and Jonathan A. Ellman -- 6.Submonomer approaches for the generation of molecular diversity: nonatural oligomer and organic template libraries. Lutz S. Richeter ... [et al] -- Part II.Small molecule libraries: overview of issues and strategies in librar design. John J. Baldwin -- 9.Protease inhibitor libraries. Dinesh V. Patel and David A. Campbell -- 10.Heterocyclic combinatorial chemistry: Azine and Diazepine pharmacophores. Michkail F. Gordeev and Dinesh V. Patel ... -- 11.Scaffolds for small molecule libraries -- 12.Application of combinatorial chemistry to biopolymers. Edmund J. Moran ... 13.Oligosaccharide and glycoconjugate solid-phase synthesis technologies for drug disocvery. Michael J. Sofia ... -- 14.Encoded combinatorial chemistry. Jeffrey W. Jacobs and Zhi-Jie Ni -- 15.Parallel organic synthesis in array format. Steven E. Hall -- 16.Synthetic organic chemsitry on solid support. Stephen W. Kaldor and Miles G. Siegel -- Part III.Automation, analytical, and computational methods -- 17.Automation of combinatorial chemistry for large libraries -- 18.Analytical chemistry issues in combinatorial organic synthesis. William L. Fitch, Gary C. Look, and George Detre -- 19.Quantifying diversity. Yvonne C. Martin, Robert D. Brown, and Mark G. Bures -- Part IV.Biological diversity -- 20.Protein scaffolds for peptide libraries. Ronald H. Hoess -- 21.Combinatorial biosynthesis of "unnatrual" natural products. Chaitan Khosla -- Part V.Screening -- 22.Strategies for screening large combinatorial libraries. Nolan H. Sigal and Daniel Chelsky -- Part VI.Combinatorial drug screening and development -- 24.Combinatorial drug screening and development. Judd Berman and Russell J. Howard -- 25.ADME/PK assays in screening for orally active drug candidates. Jacqueline Gibbons, Eric W. Taylor and Rene A. Braeckman -- 26.Combinatorial technologies: prospects and future issues. James F. Kerwin, Jr. -- 27.Appendix: Combinatorial chemistry information management. David Weininger .. |
| 520 8# - SUMMARY, ETC. |
|---|
| Summary, etc. |
This book applies combinatorial technologies to drug discovery and development and highlights the critical concept and issues that are entailed in implementation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Combinatorial chemistry. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Drugs |
| General subdivision |
Design |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pharmaceutical chemistry & technology |
| Source of heading or term |
thema |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Pharmacology |
| Source of heading or term |
thema |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Health and Wellbeing. |
| Source of heading or term |
ukslc |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Chemistry, Pharmaceutical. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Drug design. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gordon, Eric M. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kerwin, James F. |
| 902 ## - LOCAL DATA ELEMENT B, LDB (RLIN) |
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| a |
170814 |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) |
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| a |
.b1006834x |
| b |
main |
| c |
- |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Suppress in OPAC |
0 |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) |
|---|
| Operator's initials, OID (RLIN) |
1 |
| Cataloger's initials, CIN (RLIN) |
010831 |
| First Date, FD (RLIN) |
m |
| Local |
a |
| -- |
- |
| -- |
0 |