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Handbook of pharmaceutical salts : properties, selection, and use /

Handbook of pharmaceutical salts : properties, selection, and use / P. Heinrich Stahl, Camille G. Wermuth (eds.). - Weinheim ; Chichester : Wiley-VCH, c2008. - xiv, 374 p. : ill. ; 25 cm.

Includes bibliographical references and index.

Introduction (Camille G. Wernuth and P. Heinrich Stahl). Chapter 1: The Physicochemical Background: Fundamentals of Ionic Equilibria (Michael B. Maurin, David J. W. Grant and P. Heinrich Stahl). Chapter 2: Solubility and Dissolution of Weak Acids, Bases, and Salts (Madhu Pudipeddi, Abu T. M. Serajuddin, David J. W. Grant and P. Heinrich Stahl). Chapter 3: Evaluation of Solid-State Properties of Salts (Danielle Giron and David J. W. Grant). Chapter 4: Pharmaceutical Aspects of the Drug Salt Form (P. Heinrich Stahl and Masahiro Nakano). Chapter 5: Biological Effects of the Drug Salt Form (Friedlieb Pfannkuch, Harald Rettig, and P. Heinrich Stahl). Chapter 6: Salt-Selection Strategies (Abu T. M. Serajuddin and Madhu Pudipeddi). Chapter 7: A Procedure for Salt Selection and Optimization (Michael J. Bowker). Chapter 8: Large-Scale Aspects of Salt Formation: Processing of Intermediates and Final Products (Stanley Lee and Christian Hoff). Chapter 9: Patent Aspects of Drug Salt Formation (Hans-GA nther Foraita). Chapter 10: Regulatory Aspects of Drug Salts (Henning Asche, Jun-ichi Kondo, and Funmilayo O. Ajayi). Chapter 11: Selected Procedures for the Preparation of Pharmaceutically Acceptable Salts (Camille G. Wermuth and P. Heinrich Stahl). Chapter 12: Monographs on Acids and Bases (P. Heinrich Stahl and Camille G. Wermuth). Appendix (P. Heinrich Stahl).

9783906390581 (pbk.) : No price 9783906390581 (Paper)


Pharmaceutical chemistry.
Salts.
Chemistry
Clinical trials

615.19 STA

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