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Principles of gene manipulation and genomics.

Primrose, S. B.

Principles of gene manipulation and genomics. - 7th ed. / S.B. Primrose and R.M. Twyman. - Malden, Mass. ; Oxford : Blackwell, 2006. - xxii, 644 p. : ill. ; 28 cm.

Previous ed.: published as Principles of gene manipulation. 2001.

Includes bibliographical references and index.

Gene manipulation in the post-genomics era -- Basic techniques -- Cutting and joining DNA molecules -- Basic biology of plasmid and phage vectors -- Cosmids, phasmids, and other advanced vectors -- Gene cloning strategies -- Sequencing genes and short stretches of DNA -- Changing genes : site-directed mutagenesis and protein engineering -- Bioinformatics -- Cloning in bacteria other than Escherichia coli -- Cloning in Saccharomyces cerevisiaea and other fungi -- Gene transfer to animal cells -- Genetic manipulation of animals -- Gene transfer to plants -- Advanced transgenic technology -- The organization and structure of genomes -- Mapping and sequencing genomes -- Comparative genomics -- Large-scale mutagenesis and interference -- Analysis of the transcriptome -- Proteomics I : expression analysis and characterization of proteins -- Proteomics II : analysis of protein structures -- Proteomics III : protein interactions -- Metabolomics and global biochemical networks -- Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci -- Applications of recombinant DNA technology.

This text provides basic and advanced gene-manipulation techniques, genome analysis, genomics, transcriptomics, proteomics, and metabolomics, as well as the applications of these fascinating technologies.

9781405135443 (pbk.) : £29.99 1405135441 (pbk. : alk. paper)

2005018202


Nucleotide sequence.
Gene mapping.
Genomics.
Genetic engineering.
Genetic engineering
Technology.
Genetic Engineering.
Base Sequence.
Chromosome Mapping.
DNA, Recombinant.

QH442 / .O42 2006

660.65 PRI

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